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1.
Indian J Physiol Pharmacol ; 1991 Apr; 35(2): 121-4
Artigo em Inglês | IMSEAR | ID: sea-108909

RESUMO

Taste sensitivity to Phenyl-thio-Carbamide (PTC) and glucose were studied in 150 females during the 3 trimesters of their pregnancy periods. The taste sensitivity to PTC was determined by Harris and Kalmus method. For taste intensity and hedonic evaluation, 7 concentrations of glucose solutions were used. Taste sensitivity to both PTC and glucose increases during the 1st trimester of pregnancy. In comparison to non-pregnant females (from previous study) taste thresholds and hedonics decreases in pregnancy.


Assuntos
Feminino , Glucose/farmacologia , Humanos , Feniltioureia/farmacologia , Gravidez/fisiologia , Paladar/genética
2.
Indian J Physiol Pharmacol ; 1990 Jul; 34(3): 201-5
Artigo em Inglês | IMSEAR | ID: sea-106864

RESUMO

Gustatory differences in Phenylthiocarbamide (PTC) tasters and non-tasters were studied in hypothyroid and hyperthyroid subjects. After presenting for PTC sensitivity, gustatory responses to 7 dilutions of test solutions for glucose (sweet), sodium chloride (salt), citric acid (sour) and quinine sulphate (bitter) were studied in PTC tasters and non-tasters. The intensity and pleasantness responses for 4 basic tastes were measured on a 7-point and 6-point category scale respectively. Sixty percent of subjects of hyperthyroid and 40% of hypothyroid subjects were tasters. Hypothyroid subjects showed more gustatory differences as compared to hyperthyroids. The diminished intensity perception for sweet and bitter taste was much more prominent in non-tasters than tasters hypothyroids. The greater hedonic value for salt was largely observed among hypothyroid tasters.


Assuntos
Citratos/farmacologia , Ácido Cítrico , Humanos , Hipertireoidismo/fisiopatologia , Hipotireoidismo/fisiopatologia , Feniltioureia/farmacologia , Quinina/farmacologia , Cloreto de Sódio/farmacologia , Paladar/fisiologia
3.
Indian J Physiol Pharmacol ; 1983 Apr-Jun; 27(2): 92-100
Artigo em Inglês | IMSEAR | ID: sea-108944

RESUMO

The ability to taste phenylthiocarbamide (PTC) has been investigated in 422 individuals representing both sexes among the Mathur Kayastha community of Hyderabad, A.P. There is a great excess of non-tasters with a high 't' gene frequency (0.76). There is no significant difference between the males and females for the t-gene. It is suggested that the high incidence of non-tasters in Mathurs is possibly due to their Aryan origin or even endogamdus customs.


Assuntos
Adolescente , Adulto , Criança , Feminino , Humanos , Índia , Masculino , Pessoa de Meia-Idade , Fenótipo , Feniltioureia/farmacologia , Fatores Sexuais , Paladar/efeitos dos fármacos
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